Dr. Ilias Sachpazidis
Medical software engineering
Lyman-Kutcher-Burman (LKB) model for normal tissue complication probability
As an example, calculating the NTCP based on the Lyman-Kutcher-Burman (LKB) model for the endpoint of urethra stricture, we use the following parameters TD50 = 116.7 Gy, m = 0.23, n = 0.3, and α/β = 5.0 Gy. (as published by Panitierri et al.[1], and used in the study of Spohn and Sachpazidis et al.[2]).…
Centroidal Voronoi Tessellation (CVT) space partitioning
A CVT is a special type of Voronoi tessellation when each generator, of each Voronoi cell, is located in the center of the mass of the cell. CVT is an optimal partition corresponding to an optimal distribution of generators. A set is tessellated by k generators (is the position of the generator) into k Voronoi cells (denoting…
NextGen Connect Integration Engine (formely Mirth Connect)
NextGen Connect (formerly Mirth Connect) is designed for seamless healthcare message integration. It is easily configurable, easily deployed, and scalable. In one word, it is an health information and data integration engine. It solves the problem of sharing and exchanging data between healthcare applications. Data interchange is a significant problem in healthcare. There are numerous…
C-MOVE from ARIA database to ORTHANC
Let’s say that you have an installation of VARIAN ARIA database at your premises and you would like to push, over DICOM network protocol, patient’s DICOM data (e.g. imaging modalities, structures, plans, doses file) to PACS or any other DICOM network-enabled application. DICOM service configuration (on ARIA server): Before we are able to send…
Assessing radiation plan quality in quantitative way – Part I
The conformity index (CI) was first proposed in 1993 by the Radiation Therapy Oncology Group (RTOG) and described in Report 62 of the International Commission on Radiation Units and Measurements (ICRU). The conformity index, together with other evaluation indices, is a tool for analysis of a treatment plan during radiation therapy. These indices should be…